Why no mention of this study using the A Meta-Analysis and Meta-Regression methodology found good results for CBD pain mangment.
"2019 Effects of Cannabinoid Administration for Pain: A Meta-Analysis and Meta-Regression"
"When considering reductions in self-reported pain, we observed that cannabinoid administration was associated with a ‘medium-to-large’ (Cohen, 1988) pooled effect size across included studies. Importantly, cannabinoid administration was associated with statistically significant greater pain reduction than placebo administration, which yielded a ‘small-to-medium’ (Cohen, 1988) pooled effect size. Indeed, placebo administration has been shown to enhance expectations about pain reduction"
"When considering cannabis’s effect on pain, our primary meta-analysis outcomes suggest that cannabinoids may represent a viable option regarding pain management and treatment- outperforming corresponding placebo conditions across included studies."
This is extremely good evidence for pain management analysis including placebo testing.
Also most of the benefits seem to show themselves in the form of Full Spectrum Oil's and Products that include the whole plant extract rather than CBD isolates
Personally, i think a pattern of evidence for the limitations of current broad "general study" must affect All parties with little side effects are becoming clearer. We probably don't have the detailed information for specific definition relative to individual reactions, especially given how many testing regimes & biomarkers are still being defined, refined & discovered. But the pattern that we all react specifically & individually to All Medical conditions & treatments is undeniable. An approach to medication that can better account for this & give standards for individual customisation that is more informed than the current trial & error would be redefining for the industry, life-saving, & life changing for the patients involved. If we could find relative testable signs & causalities for issues, side effects, we could drastically increase treatment effectiveness & efficiency.
That poor one transplant patient who felt no changes. I imagine that using other pain relief was limited – at least for a bit. Ouch! There's a THC medication here in Canada that's used often, Nabilone. I wish there was more research and avaliable regulated pharmaceuticals that use CBD and THC
I think it's great that you highlight that there is no scientific evidence backing CBD (yet). Hope for chronic pain and illness is great but not when it means lying to patients/consumers to possibly only produce a placebo effect while gladly taking their money.
I’m curious, why are there so many studies that do not have a control group? This, along with tiny sample sizes raises the question: are these studies worth doing in the first place? I honestly don’t know, but my guess is that ethics comes into play when it comes to studies without control groups.
Unfortunately, a big part of the reason we see so few studies on the benefits (or lack of) from CBD and/or THC is due to it being a Schedule I substance (though CBD made from Hemp was recently excluded from the Controlled Substances Act). For those that don't know, a Schedule I drug is considered to have both a high risk of abuse and no medicinal value. The problem this creates is that not only is it nearly impossible to get funding for research in this area, in many cases it's actually illegal. Let's hope in the near future congress either removes marijuana/THC/CBD from the controlled substances act, or at least reclassifies it into a different schedule so we can get some serious research going.
I'm probably going to stop spending money on CBD after hearing this. I was kind of on the fence, and the effect was minimal. I think I would be better off saving the money and spending it on more massages or legal cannabis edibles when they become available, to deal with pain and anxiety.
I use CDB oil and I use a small dose, It doesn't stop all the pain but it takes most of the edge off to continue with my normal activities. I believe if I try more to stops all pain then there there is something wrong because most of my knee cartilage is mostly gone. Pain is your red line to prevent serious injuries. Common sense and science are never perfect but should be used together as partners to be the answer.
I found CBD excellent for inflammation reduction if taken at a high dose. It works even better than ibuprofen. However, as noted, it is expensive. I have many illnesses, take many medications, and wonder about CBD's possible effects on the liver. It is a shame that more studies have not been done. I don't take ibuprofen regularly because of liver, kidney, and stomach issues. For now, I wait for the trials.
My dad got addicted to pain medication after a back injury and a traumatic back surgery. It was a horrible time in all of our family. He started taking CBD tincture, which was recommended to him by a friend who was a practicing doctor, and after six months my dad was completely off of pain medication. A couple months after that he stopped taking the CBD tincture and it was truly like a miracle. I got my Dad back. I will forever be in support of CBD as a medical aid because I’ve seen how life changing it can be.
Just wanted to mention : I have a brother with a bad mental condition which trigerred multiple epileptic seizures per day. After starting on a hemp oil treatment, his seizures have decreased by 100x. This has given his brain a respite and has improved his quality of life
At 3:16 it looks like one of our sources got cut off. It should read: The American Journal of Psychiatry
Hey, while you're here, thanks for watching and have a nice day 🙂
Why no mention of this study using the A Meta-Analysis and Meta-Regression methodology found good results for CBD pain mangment.
"2019 Effects of Cannabinoid Administration for Pain: A Meta-Analysis and Meta-Regression"
"When considering reductions in self-reported pain, we observed that cannabinoid administration was associated with a ‘medium-to-large’ (Cohen, 1988) pooled effect size across included studies. Importantly, cannabinoid administration was associated with statistically significant greater pain reduction than placebo administration, which yielded a ‘small-to-medium’ (Cohen, 1988) pooled effect size. Indeed, placebo administration has been shown to enhance expectations about pain reduction"
"When considering cannabis’s effect on pain, our primary meta-analysis outcomes suggest that cannabinoids may represent a viable option regarding pain management and treatment- outperforming corresponding placebo conditions across included studies."
This is extremely good evidence for pain management analysis including placebo testing.
Also most of the benefits seem to show themselves in the form of Full Spectrum Oil's and Products that include the whole plant extract rather than CBD isolates
snake oil huh? is that why CBD was able to treat my friends alcohol withdrawal symptoms and stop his seizures. @100MG a day.
I'm helping myself with Weedborn CBD. I think this is the best medicine.
Personally, i think a pattern of evidence for the limitations of current broad "general study" must affect All parties with little side effects are becoming clearer.
We probably don't have the detailed information for specific definition relative to individual reactions, especially given how many testing regimes & biomarkers are still being defined, refined & discovered.
But the pattern that we all react specifically & individually to All Medical conditions & treatments is undeniable. An approach to medication that can better account for this & give standards for individual customisation that is more informed than the current trial & error would be redefining for the industry, life-saving, & life changing for the patients involved.
If we could find relative testable signs & causalities for issues, side effects, we could drastically increase treatment effectiveness & efficiency.
I would like for you guys to add articles references in the description. It would help greatly. Thank you
That poor one transplant patient who felt no changes. I imagine that using other pain relief was limited – at least for a bit. Ouch! There's a THC medication here in Canada that's used often, Nabilone. I wish there was more research and avaliable regulated pharmaceuticals that use CBD and THC
Better than your previous attempts at tackling this topic. Though your dislike for it is still quite intense.
It seems crazy that so many people are taking something and research funds are so nonexistent that we only test people 7 at a time.
I mean, if you gave me 300 mg of cbd that would be too much and I wouldn't be able to sleep well.
I think it's great that you highlight that there is no scientific evidence backing CBD (yet).
Hope for chronic pain and illness is great but not when it means lying to patients/consumers to possibly only produce a placebo effect while gladly taking their money.
well of course there haven't been a lot of studies… big pharma can't profit off of it
I’m curious, why are there so many studies that do not have a control group? This, along with tiny sample sizes raises the question: are these studies worth doing in the first place? I honestly don’t know, but my guess is that ethics comes into play when it comes to studies without control groups.
Unfortunately, a big part of the reason we see so few studies on the benefits (or lack of) from CBD and/or THC is due to it being a Schedule I substance (though CBD made from Hemp was recently excluded from the Controlled Substances Act). For those that don't know, a Schedule I drug is considered to have both a high risk of abuse and no medicinal value. The problem this creates is that not only is it nearly impossible to get funding for research in this area, in many cases it's actually illegal. Let's hope in the near future congress either removes marijuana/THC/CBD from the controlled substances act, or at least reclassifies it into a different schedule so we can get some serious research going.
I hope the CBD information continues to get passed on to the public, thank you for sharing this!
I'm probably going to stop spending money on CBD after hearing this. I was kind of on the fence, and the effect was minimal. I think I would be better off saving the money and spending it on more massages or legal cannabis edibles when they become available, to deal with pain and anxiety.
I use CDB oil and I use a small dose, It doesn't stop all the pain but it takes most of the edge off to continue with my normal activities. I believe if I try more to stops all pain then there there is something wrong because most of my knee cartilage is mostly gone. Pain is your red line to prevent serious injuries. Common sense and science are never perfect but should be used together as partners to be the answer.
So in the study where pain was lower in all groups, does that include the placebo group?
I need to smoke on it
May God bless Dr UROMI on YouTube for helping me to get rid of my herpes virus thanks again Dr uromi you can also message him on YouTube.
I found CBD excellent for inflammation reduction if taken at a high dose. It works even better than ibuprofen. However, as noted, it is expensive. I have many illnesses, take many medications, and wonder about CBD's possible effects on the liver. It is a shame that more studies have not been done. I don't take ibuprofen regularly because of liver, kidney, and stomach issues. For now, I wait for the trials.
There should be mention of effect size more so than sample size in your videos. Just because a sample is small doesn't mean the effect was small.
Can you do a video on palmitoylethanolamide for treating chronic pain?…. There's soooo many studies on it but I'm not sure how to interpret them all.
My dad got addicted to pain medication after a back injury and a traumatic back surgery. It was a horrible time in all of our family. He started taking CBD tincture, which was recommended to him by a friend who was a practicing doctor, and after six months my dad was completely off of pain medication. A couple months after that he stopped taking the CBD tincture and it was truly like a miracle. I got my Dad back. I will forever be in support of CBD as a medical aid because I’ve seen how life changing it can be.
Please do an episode on Ozone therapy!
Just wanted to mention : I have a brother with a bad mental condition which trigerred multiple epileptic seizures per day. After starting on a hemp oil treatment, his seizures have decreased by 100x. This has given his brain a respite and has improved his quality of life